Nasal resistance and CPAP failure
Sugiura 2007, Saitama Medical University · Clinical study
Each 0.1 Pa/cm³/s increase in nasal resistance was associated with 1.48x higher odds of CPAP failure. Association, not an Allermi outcome.
Citation on file
Sleep medicine & dental sleep
Nasal congestion is associated with difficulty tolerating CPAP and oral-appliance therapy. Addressing the nasal airway is a non-competing adjunct that may help patients stay on the therapy you have prescribed. Allermi does not treat sleep apnea and does not compete with PAP or appliances.
Peer-reviewed anchors
Sugiura 2007, Saitama Medical University · Clinical study
Each 0.1 Pa/cm³/s increase in nasal resistance was associated with 1.48x higher odds of CPAP failure. Association, not an Allermi outcome.
Citation on file
Camacho 2015 · Meta-analysis
Improved CPAP acceptance following nasal treatment in the pooled data. Establishes the nasal airway as a recognized lever in the literature.
Citation on file
Anokwute 2025, JCSM · Case report
A published case in which intranasal corticosteroid plus oxymetazoline restored PAP tolerance, closely matching Allermi's formulation. Presented as a case report, not proof of population effect.
Citation on file
10 RCTs, 400+ participants · Systematic review and meta-analysis
Saline irrigation produced a 27.7% improvement in nasal symptoms and a 62.1% reduction in medication consumption, well tolerated.
Citation on file
Allermi data, observational
95.5%
of 7,087 patients reporting nasal congestion reported improvement (AAAAI abstract; chi-square p < 0.0001; all symptoms significant except snoring).
96.6%
of 1,810 patients reporting sleep disruption reported improvement (AAAAI abstract, observational; p < 0.0001). Snoring did not reach significance.
These data are observational and are presented as supplementary to the peer-reviewed evidence above.
On framing
Patient voices
“My symptoms have significantly improved and I've been able to use my CPAP more often and for a much longer duration.”
“I use a CPAP at night, and my breathing has improved. The average number of apnea episodes has decreased, and I'm sleeping through the night.”
Individual results vary. Verified patient reviews.
Referral takes a minute. You stay the treating clinician; Allermi handles the telehealth evaluation and dispensing.