Allergy & immunology
Rhinitis is multi-mechanism, so single-mechanism therapy predictably under-treats. Allermi operationalizes what a thoughtful allergist already does by hand: an anti-inflammatory, an antihistamine, an anti-secretory agent, and a micro-dosed decongestant, tailored to the symptom profile and adjustable over time.
Peer-reviewed anchors
53 randomized controlled trials · Systematic review and meta-analysis
Combinations (INCS plus intranasal antihistamine; antihistamine plus decongestant) outperform monotherapy on nasal and ocular symptoms and quality of life.
View source →Berger 2014, n=612 · Randomized controlled trials and long-term safety study
The combination achieved markedly greater TNSS reduction than either monotherapy, with comparable safety over 52 weeks.
Citation on file
1995, n=178 · Multicenter, randomized, double-blind, placebo-controlled
Significant improvement in stuffiness, sneezing, and discharge; onset within days; well tolerated.
View source →Review · Pharmacology and efficacy review
Rapid onset and prolonged effect; effective in allergic and vasomotor rhinitis, with meaningful decongestant activity uncommon among antihistamines.
Citation on file
Multiple trials · Randomized controlled trials
Targeted control of watery rhinorrhea through an independent anticholinergic mechanism, including long-term use.
Citation on file
Baroody 2011, J Allergy Clin Immunol, n=60 · Randomized, double-blind, placebo-controlled
Fluticasone furoate plus oxymetazoline beat fluticasone alone, with no rhinitis medicamentosa in any arm over four weeks and none two weeks post-treatment.
View source →10 RCTs, 400+ participants · Systematic review and meta-analysis
Saline irrigation produced a 27.7% improvement in nasal symptoms and a 62.1% reduction in medication consumption, well tolerated.
Citation on file
Allermi data, observational
95.5%
of 7,087 patients reporting nasal congestion reported improvement (AAAAI abstract; chi-square p < 0.0001; all symptoms significant except snoring).
4.5 → 1.5
mean symptom severity on a 5-point scale at 4-week follow-up (n = 12,813), internal series.
These data are observational and are presented as supplementary to the peer-reviewed evidence above.
Patient voices
“I'd tried everything over 30-plus years. My congestion cleared, my post-nasal drip lessened, and I can finally breathe freely again.”
Individual results vary. Verified patient reviews.
Referral takes a minute. You stay the treating clinician; Allermi handles the telehealth evaluation and dispensing.
